• Corpus ID: 15133328

Thyroid autoimmunity in patients with alopecia areata.

@article{KasumagiHalilovi2008ThyroidAI,
  title={Thyroid autoimmunity in patients with alopecia areata.},
  author={Emina Kasumagi{\'c}-Halilovi{\'c}},
  journal={Acta dermatovenerologica Croatica : ADC},
  year={2008},
  volume={16 3},
  pages={
          123-5
        }
}
Alopecia areata (AA) is a common form of localized, non-scarring hair loss. It is characterized by the loss of hair in patches, total loss of scalp hair (alopecia totalis), or total loss of body hair (alopecia universalis). The etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity and endocrine dysfunction may be involved. The aim of this study was to determine whether AA is statistically associated with thyroid autoimmunity. In this retrospective… 

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References

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Thyroid disorders showed the highest frequency with on O/E ratio of 3.2 and a P value of 0.01, which is statistically highly significant, which indicates that thyroid disorders are two to three times more common in patients with alopecia areata.

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The immune studies revealed increased activated T lymphocytes in children with AA and recommend that thyroid gland size and function and antibody formation be examined at the diagnosis of AA and twice a year thereafter.

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It is indicated that individuals with alopecia areata have abnormal antibodies directed to hair follicle antigens, and this findings support the hypothesis that alop Cecilia areata is an autoimmune disease.

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The results are logically interpreted to mean that a wave of hair follicle damage or arrest moves centrifugally from a focal point beyond the area of alopecia.