Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma.

@article{Cella2012ThyroidVP,
  title={Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma.},
  author={Laura Cella and Manuel Conson and Michele Caterino and Nicola De Rosa and Raffaele Liuzzi and Marco Picardi and Francesco Maria Grimaldi and Raffaele Solla and Antonio Farella and Marco Salvatore and Roberto Pacelli},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={82 5},
  pages={1802-8}
}
PURPOSE Hypothyroidism (HT) is a frequent late side effect of Hodgkin's lymphoma (HL) therapy. The purpose of this study is to determine dose-volume constraints that correlate with functional impairment of the thyroid gland in HL patients treated with three-dimensional radiotherapy. METHODS AND MATERIALS A total of 61 consecutive patients undergoing antiblastic chemotherapy and involved field radiation treatment (median dose, 32 Gy; range, 30-36 Gy) for HL were retrospectively considered… CONTINUE READING