Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study.

Abstract

Context Increasing evidence suggests an association between thyroid-stimulating hormone (TSH), free thyroxine (fT4), and deiodinases with insulin resistance and type 2 diabetes mellitus (T2D). Objective We examined whether TSH and fT4 levels and deiodinases are causally associated with insulin resistance and T2D, using Mendelian randomization. Methods… (More)
DOI: 10.1210/jc.2016-2816

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Cite this paper

@article{Bos2017ThyroidSI, title={Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study.}, author={Maxime M Bos and R A J Smit and Stella Trompet and Diana van Heemst and Raymond Noordam}, journal={The Journal of clinical endocrinology and metabolism}, year={2017}, volume={102 6}, pages={1960-1970} }