Thyroid Nodules (≥4 cm): Can Ultrasound and Cytology Reliably Exclude Cancer?

  title={Thyroid Nodules (≥4 cm): Can Ultrasound and Cytology Reliably Exclude Cancer?},
  author={Laura I. Wharry and Kelly L. McCoy and Michael Stang and Michaele J. Armstrong and Shane O Lebeau and Mitch E. Tublin and Biatta Sholosh and Ari Silbermann and N Paul Ohori and Yuri E Nikiforov and Steven P. Hodak and Sally E. Carty and Linwah Yip},
  journal={World Journal of Surgery},
Whether a threshold nodule size should prompt diagnostic thyroidectomy remains controversial. We examined a consecutive series of patients who all had thyroidectomy for a ≥4 cm nodule to determine (1) the incidence of thyroid cancer (TC) and (2) if malignant nodules could accurately be diagnosed preoperatively by ultrasound (US), fine needle aspiration biopsy (FNAB) cytology and molecular testing. As a prospective management strategy, 361 patients with 382 nodules ≥4 cm by preoperative US had… CONTINUE READING