Thyroid Hormone Regulates the Expression of the Sonic Hedgehog Signaling Pathway in the Embryonic and Adult Mammalian Brain

@inproceedings{Desouza2011ThyroidHR,
  title={Thyroid Hormone Regulates the Expression of the Sonic Hedgehog Signaling Pathway in the Embryonic and Adult Mammalian Brain},
  author={Lynette A. Desouza and Malini Sathanoori and Richa Kapoor and Neha Rajadhyaksha and Luis Enrique Contreras Gonz{\'a}lez and Andreas Hugo Kottmann and Shubha Tole and Vidita A. Vaidya},
  booktitle={Endocrinology},
  year={2011}
}
Thyroid hormone is important for development and plasticity in the immature and adult mammalian brain. Several thyroid hormone-responsive genes are regulated during specific developmental time windows, with relatively few influenced across the lifespan. We provide novel evidence that thyroid hormone regulates expression of the key developmental morphogen sonic hedgehog (Shh), and its coreceptors patched (Ptc) and smoothened (Smo), in the early embryonic and adult forebrain. Maternal hypo- and… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 17 CITATIONS

Iodine Deficiency and the Brain: Effects and Mechanisms.

  • Critical reviews in food science and nutrition
  • 2016
VIEW 1 EXCERPT
CITES BACKGROUND

Similar Papers

Loading similar papers…