Thyroglobulin measurement in fine-needle aspirates of lymph nodes in patients with differentiated thyroid cancer: a simple definition of the threshold value, with emphasis on potential pitfalls of the method.

@article{Bournaud2010ThyroglobulinMI,
  title={Thyroglobulin measurement in fine-needle aspirates of lymph nodes in patients with differentiated thyroid cancer: a simple definition of the threshold value, with emphasis on potential pitfalls of the method.},
  author={Claire Bournaud and Anne Charri{\'e} and C{\'e}cile Nozi{\`e}res and Karim Chikh and V{\'e}ronique Lapras and M Denier and Christian Paulin and Myriam Decaussin-Petrucci and J. L. Peix and Jean-christophe Lifante and Catherine Cornu and C{\'e}line Giraud and Jacques Orgiazzi and Françoise Borson-Chazot},
  journal={Clinical chemistry and laboratory medicine},
  year={2010},
  volume={48 8},
  pages={1171-7}
}
BACKGROUND Thyroglobulin measurements in fine-needle aspirate (FNA-Tg) is an accurate method for the diagnosis of lymph node metastasis in differentiated thyroid carcinoma. The goal of this study is to determine the most appropriate diagnostic threshold value for FNA-Tg. METHODS Ultrasound-guided fine-needle aspiration-cytology (FNA-C) and FNA-Tg were performed on suspicious lymph nodes in 114 consecutive patients with thyroid cancer prior to thyroidectomy (n=13) or during follow-up (n=93… CONTINUE READING
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