Thymus transplantation.

@article{Markert2010ThymusT,
  title={Thymus transplantation.},
  author={M. Louise Markert and Blythe H. Devlin and Elizabeth A McCarthy},
  journal={Clinical immunology},
  year={2010},
  volume={135 2},
  pages={236-46}
}
Thymus transplantation is a promising investigational therapy for infants born with no thymus. Because of the athymia, these infants lack T cell development and have a severe primary immunodeficiency. Although thymic hypoplasia or aplasia is characteristic of DiGeorge anomaly, in "complete" DiGeorge anomaly, there is no detectable thymus as determined by the absence of naive (CD45RA(+), CD62L(+)) T cells. Transplantation of postnatal allogeneic cultured thymus tissue was performed in sixty… CONTINUE READING
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