Thymus mastichina: Chemical Constituents and their Anti-Cancer Activity

  title={Thymus mastichina: Chemical Constituents and their Anti-Cancer Activity},
  author={J. Gordo and P. M{\'a}ximo and E. Cabrita and A. Lourenço and A. Oliva and J. Almeida and M. Filipe and P. Cruz and R. B{\'a}rcia and Miguel M Santos and H. Cruz},
  journal={Natural Product Communications},
The cytotoxicity-guided study of the dichloromethane and ethanol extracts of Thymus mastichna L. using the HCT colon cancer cell line allowed the identification of nine compounds, sakuranetin (1), sterubin (2), oleanolic acid (3), ursolic acid (4), lutein (5), β-sitosterol (6), rosmarinic acid (7), 6-hydroxyluteolin-7-O-β-glucopyranoside (8), and 6-hydroxyapigenin-7-O-β-glucopyranoside (9). All compounds were tested for their cytotoxicity against the HCT colon cancer cell line. Compound 4… Expand

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