Thymus and pulmonary lymph node response to acute and subchronic ozone inhalation in the mouse.

@article{Dziedzic1986ThymusAP,
  title={Thymus and pulmonary lymph node response to acute and subchronic ozone inhalation in the mouse.},
  author={Dariusz Dziedzic and H. J. White},
  journal={Environmental research},
  year={1986},
  volume={41 2},
  pages={598-609}
}
Ozone is an oxidant gas which primarily injures the centroacinar portion of the lung. While the classical lesion of oxidant-mediated lung damage is relatively well described, the effect of this form of injury on the lymphocytic arm of the pulmonary defense system is less clear. In the present experiments we exposed CD-1 female mice to ozone at a level of 0.7 ppm for 20 hr per day for 1-28 days and observed the lymphocyte response in the pulmonary lymph nodes and the thymus. In the mediastinal… CONTINUE READING

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