Thymosin beta 4 improves dermal burn wound healing via downregulation of receptor of advanced glycation end products in db/db mice.

@article{Kim2014ThymosinB4,
  title={Thymosin beta 4 improves dermal burn wound healing via downregulation of receptor of advanced glycation end products in db/db mice.},
  author={Sokho Kim and Jungkee Kwon},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1840 12},
  pages={
          3452-9
        }
}
BACKGROUND The delay of dermal burn wound healing caused by vascular disorders is a critical problem for many diabetic patients. Thymosin β4 (Tβ4), identified by subtractive cloning of endothelial cells on plastic versus basement membrane substrates, has been found to promote angiogenesis and dermal wound repair in rats, aged mice, and db/db diabetic mice. However, previous studies involving the role of Tβ4 in wound repair were limited to mechanical damage and dermal impairment. Thus, this… CONTINUE READING

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