Thymosin alpha 1 as an adjunct to influenza vaccination in the elderly: rationale and trial summaries.

@article{Ershler2007ThymosinA1,
  title={Thymosin alpha 1 as an adjunct to influenza vaccination in the elderly: rationale and trial summaries.},
  author={William B. Ershler and Stefan Gravenstein and Zeba S Geloo},
  journal={Annals of the New York Academy of Sciences},
  year={2007},
  volume={1112},
  pages={375-84}
}
From a clinical perspective, the immune deficiency of aging (immune senescence) is not profound. In fact, it may be of little clinical consequence. However, older people are prone to chronic and debilitating disorders which alone, or in concert with the medications used in their treatment, may add to the age effect and create a more clinically relevant immune deficiency. As a result, many older people are susceptible to infection. Furthermore, it is now well recognized that older people respond… CONTINUE READING