Thymoquinone exerts neuroprotective effect in animal model of Parkinson's disease.

  title={Thymoquinone exerts neuroprotective effect in animal model of Parkinson's disease.},
  author={Seyedeh Shohreh Ebrahimi and Shahrbanoo Oryan and Esmael Izadpanah and Kambiz Hassanzadeh},
  journal={Toxicology letters},
Oxidative stress plays an important role in both the initiation and progression of Parkinson's disease (PD). Rotenone, an environmental toxin, induces oxidative stress and impact mitochondrial dynamics, including fission and fusion. Thymoquinone (TQ) has been reported to have antioxidant and anti-inflammatory characteristics in vitro and in vivo. TQ scavenges free radicals so prevents cell damage against oxidative agents. To evaluate the efficacy of TQ in the management of PD, male Wistar rats… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 27 references

Parkinson's disease

  • Silachev, D.N, +17 authors D.B
  • J Neurosci Rural Pract
  • 2015
Highly Influential
15 Excerpts

Mechanisms of the hydroxyl and superoxide anion radical scavenging activity and protective effect on lipid peroxidation of thymoquinone: a DFT study

  • Akhtari, Hassanzadeh, Fakhraei, Zarei, S.A
  • 2014
1 Excerpt

Apoptosis: an international journal on programmed cell death

  • Zhang, Xue, +8 authors Y.Q
  • Cell Mol Neurobiol
  • 2013
1 Excerpt

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