Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats.

@article{ElSaleh2004ThymoquinoneAN,
  title={Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats.},
  author={Saleh C El-Saleh and Othman A. Al-Sagair and Maha I Al-Khalaf},
  journal={International journal of cardiology},
  year={2004},
  volume={93 1},
  pages={
          19-23
        }
}
Although the state of hyperhomocysteinemia (HHcy) appears to be associated with higher risks of coronary, cerebral and peripheral vascular disease as well as with a number of other clinical conditions, the underlying molecular mechanisms are not fully elucidated. There is strong evidence, however, that HHcy could induce a pathogenic state of oxidative stress. The interest in modulating the elevated levels of total homocysteine in HHcy and/or their negative impacts through preventive strategies… CONTINUE READING