Thymoma-associated multiorgan autoimmunity: a graft-versus-host-like disease.

  title={Thymoma-associated multiorgan autoimmunity: a graft-versus-host-like disease.},
  author={Akhil Wadhera and Emanual Maverakis and Nicholas S. Mitsiades and Primo N. Lara and Maxwell A Fung and Peter J Lynch},
  journal={Journal of the American Academy of Dermatology},
  volume={57 4},
Graft-versus-host disease (GVHD) is a T cell-mediated disease seen most commonly after hematopoietic stem cell transplantation. Rarely, a GVHD-like disease can be seen in patients with malignant thymoma. We describe a 50-year-old man with malignant thymoma who developed skin, liver, and intestinal manifestations similar to that seen in GVHD. We also review other reported cases of GVHD-like manifestations in the setting of thymoma and propose "thymoma-associated multiorgan autoimmunity" as a… CONTINUE READING