Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma

@inproceedings{Lee2010ThymidineST,
  title={Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma},
  author={S Y Lee and Y H Park and KyuJin Kim and E Y Cho and Y C Ahn and K. Kim and Y Michael Shim and J S Ahn and Keun-Joon Park and Y H Im},
  booktitle={British Journal of Cancer},
  year={2010}
}
Background:Our purpose was to evaluate thymidine synthase (TS), thymidine phosphorylase (TP), and excision repair cross-complementation group 1 (ERCC1) expression as biomarkers for capecitabine and cisplatin (XP) combination chemotherapy in patients with metastatic oesophageal squamous cell cancer.Method:A total of 113 patients with metastatic oesophageal squamous cell cancer were treated with XP chemotherapy at the Samsung Medical Center between 2003 and 2007, of whom 72 had available clinical… CONTINUE READING
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Upper Gastrointestinal Clinical Studies Group of the National Cancer

  • D Cunningham, N Starling, +7 authors AR Norman
  • Research Institute of the United Kingdom
  • 2008
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