Thymidine kinase: an inexpensive index of liver regeneration in a large animal model.

  title={Thymidine kinase: an inexpensive index of liver regeneration in a large animal model.},
  author={Delawir Kahn and Jochen Stadler and John Terblanche and R V van Hoorn-Hickman},
  volume={79 5 Pt 1},
Most studies of liver regeneration have been restricted to small animals because of the cost of assessment of DNA synthesis by the standard method of thymidine incorporation in vivo. This paper presents the use of thymidine kinase as an inexpensive measure of regeneration in large animals. The use of the large model is advantageous because of the availability of serial blood and tissue samples from the same animal. Initially, the responses in thymidine kinase and thymidine incorporation over a… CONTINUE READING


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