Thymic stromal lymphopoietin and cancer.

  title={Thymic stromal lymphopoietin and cancer.},
  author={Emma Lo Kuan and Steven F. Ziegler},
  journal={Journal of immunology},
  volume={193 9},
Originally shown to promote the growth and activation of B cells, thymic stromal lymphopoietin (TSLP) is now known to have wide-ranging effects on both hematopoietic and nonhematopoietic cell lineages. These include dendritic cells, basophils, mast cells, B cells, epithelial cells, and CD4(+), CD8(+), and NK T cells. Although TSLP's role in the promotion of Th2 responses has been studied extensively in the context of lung- and skin-specific allergic disorders, it is becoming increasingly clear… CONTINUE READING
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