Thymic involution in murine graft-versus-host reaction. Epithelial injury mimicking human thymic dysplasia.

@article{Seemayer1977ThymicII,
  title={Thymic involution in murine graft-versus-host reaction. Epithelial injury mimicking human thymic dysplasia.},
  author={Thomas A. Seemayer and Wayne S. Lapp and Robert P Bolande},
  journal={The American journal of pathology},
  year={1977},
  volume={88 1},
  pages={119-34}
}
Mild, moderate, and severe graft-versus-host (GVH) reactions were induced in four series of experiments in 71 CBA X A and C57BL/6 X A F1 hybrid mice. At regular intervals post-GVH reaction induction (Days 4-42), the animals were sacrificed, autopsied, and histologically studied. Visceral alterations of GVH reaction were recorded in the spleen, lymph nodes… CONTINUE READING