Thy-1 associated pp85--90 is a potential docking site for SH2 domain-containing signal transduction molecules.

@article{Durrheim2001Thy1AP,
  title={Thy-1 associated pp85--90 is a potential docking site for SH2 domain-containing signal transduction molecules.},
  author={Glenda A. Durrheim and Debra Garnett and Kevin M. Dennehy and A D Beyers},
  journal={Cell biology international},
  year={2001},
  volume={25 1},
  pages={33-42}
}
Thy-1, a glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at high levels on thymocytes, has been implicated in positive and negative signal transduction. We show that Thy-1 associates with a protein of 85--90 kDa, which is prominently phosphorylated in vitro as well as in vivo following the stimulation of thymocytes with pervanadate. pp85--90 is not identical to known proteins that are phosphorylated following T cell activation. The SH2 domains of fyn, csk… CONTINUE READING

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