Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain.

@article{Stingl1987Thy1DE,
  title={Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain.},
  author={Georg Stingl and Frits Koning and Hiroshi Y Yamada and Wayne M Yokoyama and Erwin Tschachler and Jeffrey A Bluestone and Guido Steiner and Lawrence E Samelson and Andrew M. Lew and John E. Coligan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 13},
  pages={4586-90}
}
The murine epidermis is a heterogeneous epithelium composed of keratinocytes, melanocytes, Langerhans cells, and a recently described subpopulation (2-3%) of bone-marrow-derived leukocytes with a dendritic morphology and the cell surface phenotype Thy-1+, L3T4-, Lyt-2-. Previous studies have demonstrated that cell lines derived from freshly explanted Thy-1+ dendritic epidermal cells (DEC) have abundant mRNA for rearranged T-cell receptor (TCR) gamma-chain genes. Analysis of Thy-1+ DEC in situ… CONTINUE READING

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