Thrombotic thrombocytopenic purpura in children.


PURPOSE OF REVIEW Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening disease in children, due to a severe deficiency of ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 repeats, member 13), inherited in congenital TTP or secondary to anti-ADAMTS13 antibodies in acquired TTP. Rapid techniques for ADAMTS 13 assays… (More)
DOI: 10.1097/MOP.0b013e32835e7888

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