Thrombotic thrombocytopenic purpura and its diagnosis.

  title={Thrombotic thrombocytopenic purpura and its diagnosis.},
  author={Agn{\`e}s Veyradier and Dominique Meyer},
  journal={Journal of thrombosis and haemostasis : JTH},
  volume={3 11},
Thrombotic thrombocytopenic purpura (TTP) is a lifethreatening illness whose mortality rate exceeds 90% in the absence of rapid appropriate treatment. Empirical plasmatherapy instituted in the 1970s has reduced the death rate to approximately 25% and both plasma infusions and plasma exchanges remain the only efficient treatments so far. TTP prevalence is about four per one million with a preference for women of childbearing age [1]. To diagnose TTP implies to face a first challenge: to define… CONTINUE READING