Thrombotic thrombocytopenic purpura and HIV infection.

  title={Thrombotic thrombocytopenic purpura and HIV infection.},
  author={Quyen D. Chu and L Jeffrey Medeiros and A E Fisher and R F Chaquette and James P. Crowley},
  journal={Southern medical journal},
  volume={88 1},
We report on a man who was HIV-seropositive and who was initially admitted following multiple episodes of syncope. He gradually developed fulminant thrombotic thrombocytopenic purpura (TTP). Twenty-one patients with TTP who were HIV-positive have been reported previously. Of these 22 patients, all treated with plasmapheresis, 7 died from TTP and 3 suffered relapse but eventually recovered. Delay in initiating plasmapheresis may be fatal. We have correlated the laboratory data of these patients… CONTINUE READING