Thrombotic thrombocytopenic purpura: prospective neurologic, neuroimaging and neurophysiologic evaluation.

@article{Meloni2001ThromboticTP,
  title={Thrombotic thrombocytopenic purpura: prospective neurologic, neuroimaging and neurophysiologic evaluation.},
  author={Giovanna Meloni and Anna Proia and Giovanni Antonini and C De Lena and Vito Guerrisi and Saveria Capria and Silvia Maria Trisolini and Giancarlo Ferrazza and Giulio Sideri and Franco Mandelli},
  journal={Haematologica},
  year={2001},
  volume={86 11},
  pages={
          1194-9
        }
}
BACKGROUND AND OBJECTIVES Neurologic symptoms are present in 60% of patients with thrombotic thrombocytopenic purpura (TTP) on initial examination and ultimately develop in about 90% of cases during the course of the disease. Despite central nervous system involvement being frequent, abnormalities in the brain of patients with TTP are infrequent on neuroimaging (CT/MRI) and neurophysiologic (EEG) evaluation, often reversible and mainly limited to symptomatic stages of the disease. The aim of… CONTINUE READING

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