Thrombotic microangiopathies: new insights and new challenges

@article{Zipfel2010ThromboticMN,
  title={Thrombotic microangiopathies: new insights and new challenges},
  author={P. Zipfel and S. Heinen and C. Skerka},
  journal={Current Opinion in Nephrology and Hypertension},
  year={2010},
  volume={19},
  pages={372–378}
}
Purpose of reviewThrombotic microangiopathies (TMAs) manifest as a spectrum of related disorders in the form of thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). New data on both diseases support more and more the relatedness of the disorders and reveal related pathomechanisms, which, however, manifest in different organs. TTP develops primarily at neurological sites, and also in the kidney, and HUS is a kidney disease. In TTP thrombi formation occurs subsequently to the… Expand
48 Citations
Von Willebrand Factor-Mediated Thrombotic Microangiopathies
  • Highly Influenced
  • PDF
5 Von Willebrand Factor-Mediated Thrombotic Microangiopathies
  • Highly Influenced
  • PDF
Viral-associated thrombotic microangiopathies.
  • 30
  • PDF
Investigational drugs in thrombotic thrombocytopenic purpura
  • 9
Treatment of atypical hemolytic uremic syndrome and thrombotic microangiopathies: a focus on eculizumab.
  • 83
Thrombotic microangiopathies: role of ADAMTS-13.
  • 1
  • PDF
Atypical Hemolytic Uremic Syndrome: Differential Diagnosis from TTP/HUS and Management
  • M. Yenerel
  • Medicine
  • Turkish journal of haematology : official journal of Turkish Society of Haematology
  • 2014
  • 7
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 84 REFERENCES
The molecular biology of thrombotic microangiopathy.
  • H. Tsai
  • Medicine
  • Kidney international
  • 2006
  • 122
Pathophysiology of thrombotic thrombocytopenic purpura
  • H. Tsai
  • Medicine
  • International journal of hematology
  • 2010
  • 223
Autoantibodies in haemolytic uraemic syndrome (HUS).
  • 83
von Willebrand factor, ADAMTS-13, and thrombotic thrombocytopenic purpura.
  • J. Moake
  • Medicine
  • Seminars in hematology
  • 2004
  • 189
Thrombomodulin mutations in atypical hemolytic-uremic syndrome.
  • 314
Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome.
  • 454
  • PDF
Thrombotic Microangiopathies
  • 338
  • PDF
Complement factor H mutation in familial thrombotic thrombocytopenic purpura with ADAMTS13 deficiency and renal involvement.
  • 125
  • PDF
...
1
2
3
4
5
...