Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepatocytes.

@article{Robson1995ThrombospondinrelatedAP,
  title={Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepatocytes.},
  author={Kathryn Robson and Ute Frevert and Inge Reckmann and Graeme Cowan and J. Beier and Ian G. Scragg and Kazuaki Takehara and David H. L. Bishop and Gabriele Pradel and Robert E Sinden},
  journal={The EMBO journal},
  year={1995},
  volume={14 16},
  pages={3883-94}
}
Plasmodium sporozoites collected from oocysts, haemocoel and salivary glands of the mosquito show profound differences in their biological properties such as motility, ability to induce protective immune response and infectivity for vertebrate host cells. Sporozoites from salivary glands are much more infectious than those from oocysts and haemocoel. Differential expression of proteins, such as the circumsporozoite (CS) protein and the thrombospondin-related adhesive protein (TRAP), implicated… CONTINUE READING