Thrombospondin-1 inhibits ossification of tissue engineered cartilage constructed by ADSCs.

@article{Xie2017Thrombospondin1IO,
  title={Thrombospondin-1 inhibits ossification of tissue engineered cartilage constructed by ADSCs.},
  author={Aiguo Xie and Jixin Xue and Gan Shen and Lanjun Nie},
  journal={American journal of translational research},
  year={2017},
  volume={9 7},
  pages={3487-3498}
}
Cartilage tissue engineering provides a new method in the treatment of cartilage defects, and adipose derived stem cells seem to be an ideal seed cell in cartilage tissue engineering because of its characteristics. However, ossification after in vivo implantation of tissue engineered cartilage remains a challenge. Thrombospondin-1 which has been reported to have an inhibitory effect on angiogenesis, may play an important role in inhibiting the ossification of tissue engineered cartilage… CONTINUE READING