Thromboprophylaxis by low-molecular-weight heparin in elective hip surgery. A placebo controlled study.

@article{Trholm1991ThromboprophylaxisBL,
  title={Thromboprophylaxis by low-molecular-weight heparin in elective hip surgery. A placebo controlled study.},
  author={Carsten T\orholm and L Broeng and Per Seest J\orgensen and Peter Bjerregaard and L Josephsen and P K J\orgensen and Kikke Kirsten Hagen and Jens Bjerre Knudsen},
  journal={The Journal of bone and joint surgery. British volume},
  year={1991},
  volume={73 3},
  pages={434-8}
}
In a double-blind, randomised study of thromboprophylaxis in patients undergoing total hip replacement, we compared a low-molecular-weight heparin with a placebo. Of the 120 patients enrolled, 112 completed the trial; 58 in the treatment group and 54 in the placebo group. Nine (16%) patients in the treatment group and 19 (35%) in the placebo group developed deep venous thrombosis, diagnosed by the 125I-fibrinogen uptake test (p < 0.02). Verification was obtained by phlebography in 86% of the… CONTINUE READING

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