Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors.

@article{Chen2004ThrombopoietinCW,
  title={Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors.},
  author={Wei Hua Chen and Svetlana Antonenko and Joel M Sederstrom and Xueqing Liang and Anissa S. H. Chan and Holger Kanzler and Bianca Blom and Bruce R Blazar and Yong-Jun Liu},
  journal={Blood},
  year={2004},
  volume={103 7},
  pages={2547-53}
}
Type 1 interferon-producing cells (IPCs), also known as plasmacytoid dendritic cell (DC) precursors, represent the key effectors in antiviral innate immunity and triggers for adaptive immune responses. IPCs play important roles in the pathogenesis of systemic lupus erythematosus (SLE) and in modulating immune responses after hematopoietic stem cell transplantation. Understanding IPC development from hematopoietic progenitor cells (HPCs) may provide critical information in controlling viral… CONTINUE READING
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