Thrombolytic therapy within 3 to 6 hours after onset of ischemic stroke: useful or harmful?

@article{Ringleb2002ThrombolyticTW,
  title={Thrombolytic therapy within 3 to 6 hours after onset of ischemic stroke: useful or harmful?},
  author={P A Ringleb and Peter Dieter Schellinger and Corinna Schranz and Werner Hacke},
  journal={Stroke},
  year={2002},
  volume={33 5},
  pages={1437-41}
}
BACKGROUND The use of recombinant tissue plasminogen activator (rtPA) within 3 hours after onset of an ischemic stroke is an established therapy. Because the use of intravenous rtPA beyond a time window of 3 hours after stroke onset is still a matter of debate, we sought to review the evidence for the use of thrombolytic therapy in a time window up to 6 hours after onset of symptoms of ischemic stroke. SUMMARY OF REVIEW The meta-analyses of the major trials (National Institute of Neurological… CONTINUE READING

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