Thrombolytic therapy with tissue plasminogen activator or streptokinase induces transient thrombin activity.

@article{Owen1988ThrombolyticTW,
  title={Thrombolytic therapy with tissue plasminogen activator or streptokinase induces transient thrombin activity.},
  author={Jonathan S Owen and K D Friedman and B A Grossman and Carrye Wilkins and Ayse Berke and Eric R. Powers},
  journal={Blood},
  year={1988},
  volume={72 2},
  pages={616-20}
}
We have determined the plasma level of fibrinopeptide A as a specific index of thrombin activity during the infusion of a thrombolytic agent in patients with acute myocardial infarction. Peripheral venous plasma levels of fibrinopeptide A increased following the initiation of thrombolytic therapy from 2.7 nmol/L to a peak of 13.0 nmol/L at 30 minutes with… CONTINUE READING