Thrombolytic therapy of massive pulmonary embolism during prolonged cardiac arrest using recombinant tissue-type plasminogen activator.

@article{Langdon1989ThrombolyticTO,
  title={Thrombolytic therapy of massive pulmonary embolism during prolonged cardiac arrest using recombinant tissue-type plasminogen activator.},
  author={R W Langdon and W R Swicegood and David A Schwartz},
  journal={Annals of emergency medicine},
  year={1989},
  volume={18 6},
  pages={
          678-80
        }
}
Cardiac arrest caused by massive pulmonary embolism is highly refractory to conventional resuscitation. Emergency surgical embolectomy has been considered the only effective intervention. We present the case of a 33-year-old woman who suffered a massive pulmonary embolism with circulatory arrest refractory to one half hour of aggressive CPR. A 10-mg bolus of recombinant tissue-type plasminogen activator was administered through a central line followed by a further 90-mg IV infusion over two… CONTINUE READING
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