Thrombolysis-related intracranial hemorrhage: a radiographic analysis of 244 cases from the GUSTO-1 trial with clinical correlation. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.

@article{Gebel1998ThrombolysisrelatedIH,
  title={Thrombolysis-related intracranial hemorrhage: a radiographic analysis of 244 cases from the GUSTO-1 trial with clinical correlation. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries.},
  author={James M Gebel and Cathy A. Sila and Michael A. Cusumano Sloan and Christopher B. Granger and Kenneth W. Mahaffey and Joseph P Weisenberger and Cindy L. Green and Harvey Douglas White and Joel M. Gore and William D. Weaver and Robert M. Califf and Eric J. Topol},
  journal={Stroke},
  year={1998},
  volume={29 3},
  pages={563-9}
}
BACKGROUND AND PURPOSE Intracranial hemorrhage (ICH) is a serious complication of thrombolytic therapy. We systematically reviewed the radiographic features of 244 cases of symptomatic ICH complicating thrombolysis for acute myocardial infarction in the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO-1) trial, correlated these observations with clinical data, and speculated on hemorrhage pathogenesis. METHODS CT scans from 244… CONTINUE READING
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