Thrombolysis in acute ischaemic stroke

  title={Thrombolysis in acute ischaemic stroke},
  author={Amanda C{\'a}ceres Pereira and Paul J Martin and Elizabeth A. Warburton},
The primary deficit in acute ischaemic stroke is one of impaired blood flow. Part of the cerebral circulation is occluded either by in situ thrombosis, or embolism from the heart or a more proximal artery (for example, the ipsilateral internal carotid artery). Angiographic studies of the cerebral circulation in acute stroke demonstrate occluding thrombus in up to 80% of patients. The aim of thrombolytic therapy therefore is to lyse an occluding thrombus or embolus and reduce the volume of… CONTINUE READING