Thrombolysis for experimental deep venous thrombosis maintains valvular competence and vasoreactivity.

@article{Rhodes2000ThrombolysisFE,
  title={Thrombolysis for experimental deep venous thrombosis maintains valvular competence and vasoreactivity.},
  author={Jeffrey M Rhodes and Jae Sung Cho and P{\'e}ter Gloviczki and Geza I Mozes and Roderick L. Rolle and Virginia M Miller},
  journal={Journal of vascular surgery},
  year={2000},
  volume={31 6},
  pages={1193-205}
}
PURPOSE Thrombolysis protects the structural and functional integrity of vein wall in an experimental model of acute deep venous thrombosis (DVT) immediately after treatment, but late sequelae have not been studied. We designed experiments to compare the effects of thrombolysis and surgical thrombectomy at 4 weeks after the treatment of DVT. METHODS DVT was produced bilaterally in male mongrel dogs by proximal and distal femoral vein ligation. Five dogs underwent sham operation. After 48… CONTINUE READING

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