Thrombogenesis in Membrane Oxygenators and Adsorption Devices

  title={Thrombogenesis in Membrane Oxygenators and Adsorption Devices},
  author={Ronald M. Lindsay and Jan Feijen and Powell Millington},
Thrombus formation on foreign surfaces is a complex process initiated by two main mechanisms: platelet retention and coagulation. The final result is fibrin formation and loss of formed elements. It is unlikely that there will ever be an extracorporeal circuit available which will be able to function with the same characteristics as the vascular system. Thus, the general aim must be to understand the mechanisms involved in order to minimise thrombogenesis either by modification of the surface… CONTINUE READING