Thromboembolic events lead to cortical spreading depression and expression of c-fos, brain-derived neurotrophic factor, glial fibrillary acidic protein, and heat shock protein 70 mRNA in rats.

@article{Dietrich2000ThromboembolicEL,
  title={Thromboembolic events lead to cortical spreading depression and expression of c-fos, brain-derived neurotrophic factor, glial fibrillary acidic protein, and heat shock protein 70 mRNA in rats.},
  author={W. Dalton Dietrich and Jessie S. Truettner and Ricardo Prado and Nancy E Stagliano and Weizhao Zhao and Raul Busto and Myron D. Ginsberg and Brant D. Watson},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2000},
  volume={20 1},
  pages={103-11}
}
The hypotheses that cerebral embolic events lead to repetitive episodes of cortical spreading depression (CSD) and that these propagating waves trigger the expression of c-fos, brain-derived neurotrophic factor (BDNF), glial fibrillary acidic protein (GFAP), and heat shock protein 70 (HSP70) mRNA were tested. Wistar rats underwent photochemically induced right common carotid artery thrombosis (CCAT) (n = 18) or sham (n = 8) procedures. In a subgroup of rats (n = 5), laser-Doppler flowmetry… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Estradiol differentially regulates c-Fos after focal cerebral ischemia.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2003
View 10 Excerpts
Highly Influenced

Functional differentiation of multiple perilesional zones after focal cerebral ischemia.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2000
View 1 Excerpt

Similar Papers

Loading similar papers…