Thrombin mitogenic responses and protein phosphorylation are different in cultured human endothelial cells derived from large and microvessels.

@article{Dupuy1989ThrombinMR,
  title={Thrombin mitogenic responses and protein phosphorylation are different in cultured human endothelial cells derived from large and microvessels.},
  author={Evelyne Dupuy and Andreas Bikfalvi and Francine Rendu and Stuart Toledano and G{\'e}rard Tobelem},
  journal={Experimental cell research},
  year={1989},
  volume={185 2},
  pages={363-72}
}
It is well established that thrombin induces various biological responses in endothelial cells derived from large vessels. However, little is known about the effects of thrombin on the microvasculature. Protein phosphorylation may be one of the mechanisms by which an extracellular stimulus initiates cellular events like proliferation. Therefore, we have… CONTINUE READING