Thrombin inhibition by antithrombin in the presence of oversulfated dermatan sulfates.

@article{Maaroufi2006ThrombinIB,
  title={Thrombin inhibition by antithrombin in the presence of oversulfated dermatan sulfates.},
  author={Raoui Mounir Maaroufi and Marcel Jozefowicz and Jacqueline Tapon-Bretaudi{\`e}re and A M Fischer},
  journal={Carbohydrate research},
  year={2006},
  volume={341 5},
  pages={672-6}
}
DSS1 and DSS2 are two oversulfated dermatan sulfate derivatives with sulfur contents of 7.8% and 11.5%, respectively. DSS1 and DSS2 both enhanced the rate at which antithrombin (AT) inactivates thrombin according to a concentration dependent manner. The analysis of the experimental data, using our previously described kinetic model [Biomaterials1997, 18… CONTINUE READING