Thrombin generation in hemorrhage control and vascular occlusion.

  title={Thrombin generation in hemorrhage control and vascular occlusion.},
  author={Kenneth G. Mann},
  volume={124 2},
Hippocrates and Aristotle recognized that blood clots outside the body, but it was not until 1720 that John Louis Petit recognized that control of hemorrhage after amputation was associated with the blood clotting process.1 One hundred thirty-eight years later, Rudolph Virchow formulated his postulates regarding clots in venous thrombosis.2 The association of blood clots with acute arterial occlusion was advanced by James B. Herrick3 in 1912, but the significance of blood clotting in acute… CONTINUE READING
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Coagulation Explosion, Part 1: Initiation [video

  • KG Mann
  • http://www. RP1eLdkdJKg…
  • 2010

Coagulation Explosion, Part II: Propagation [video]. http:// oj9E33BZMsI

  • KG Mann
  • Accessed December
  • 2010

The effects of flow on the activation of bovine prothrombin by prothrombinase at physiologically relevant shear rates

  • LM Haynes, Y Dubief, T Orfeo, KG. Mann
  • FASEB J. 2010;24(suppl):835.4
  • 2010

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