Thrombin and trypsin receptors: the same mechanism of signalling on cellular surfaces.

@article{Olejr1999ThrombinAT,
  title={Thrombin and trypsin receptors: the same mechanism of signalling on cellular surfaces.},
  author={Tom{\'a}{\vs} Olej{\'a}r and K. Nouza},
  journal={Bratislavske lekarske listy},
  year={1999},
  volume={100 2},
  pages={
          75-9
        }
}
Proteinase-activated receptors (PARs), ubiquitous surface molecules participating on many biological processes have been recently discovered. Specific receptors for thrombin (PAR-1 and PAR-3) and trypsin (PAR-2) are described in this review. They belong to a family of G protein-coupled receptors activated by amino acid sequence of N-terminal part of bound ligand revealed by site-specific proteolysis. PARs participate in tissue growth and differentiation, regeneration and reparation… CONTINUE READING

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