Thrombin activatable fibrinolysis inhibitor and an antifibrinolytic pathway.

  title={Thrombin activatable fibrinolysis inhibitor and an antifibrinolytic pathway.},
  author={Laszlo Bajzar},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={20 12},
  • Laszlo Bajzar
  • Published 2000 in
    Arteriosclerosis, thrombosis, and vascular…
Coagulation and fibrinolysis are processes that form and dissolve fibrin, respectively. These processes are exquisitely regulated and protect the organism from excessive blood loss or excessive fibrin deposition. Regulation of these cascades is accomplished by a variety of mechanisms involving cellular responses, flow, and protein-protein interactions. With respect to regulation mediated by protein-protein interaction, the coagulation cascade appears to be more complex than the fibrinolytic… CONTINUE READING


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Inhibition of activated TAFI (thrombin-activatable fibrinolysis inhibitor) enhances tissue plasminogen activator-induced thrombolysis in a rabbit jugular vein thrombolysis model

  • M Nagashima, M Werner, +4 authors P. Verhallen
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