Thrombin A-Chain: Activation Remnant or Allosteric Effector?

Abstract

Although prothrombin is one of the most widely studied enzymes in biology, the role of the thrombin A-chain has been neglected in comparison to the other domains. This paper summarizes the current data on the prothrombin catalytic domain A-chain region and the subsequent thrombin A-chain. Attention is given to biochemical characterization of naturally… (More)
DOI: 10.1155/2010/416167

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