Thrombin/antithrombin III complex formation in the neonatal respiratory distress syndrome.

@article{Schmidt1992ThrombinantithrombinIC,
  title={Thrombin/antithrombin III complex formation in the neonatal respiratory distress syndrome.},
  author={Barbara K Schmidt and Patsy Vegh and J{\"u}rgen Weitz and Marilyn Johnston and Chris Caco and Richard Roberts},
  journal={The American review of respiratory disease},
  year={1992},
  volume={145 4 Pt 1},
  pages={767-70}
}
Intravascular and intra-alveolar thrombin generation may exacerbate the pulmonary hypertension and surfactant dysfunction that characterize the neonatal respiratory distress syndrome (RDS). Although low levels of the most important thrombin inhibitor, antithrombin III (AT III), have been reported in infants with RDS, direct evidence of increased intravascular thrombin generation has been lacking. Accordingly, the objective of this study was to determine whether thrombin generation is increased… CONTINUE READING