Threoninol as a scaffold of dyes (threoninol-nucleotide) and their stable interstrand clustering in duplexes.

Abstract

Functional molecules such as dyes (Methyl Red, azobenzene, and Naphthyl Red) were tethered on D-threoninol as base surrogates (threoninol-nucleotide), which were consecutively incorporated at the center of natural oligodeoxyribonucleotides (ODNs). Hybridization of two ODNs involving threoninol-nucleotides allowed interstrand clustering of the dyes on D… (More)
DOI: 10.1039/b806406g

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