Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.

@article{Vincenti2012ThreeyearOF,
  title={Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.},
  author={Flavio G. Vincenti and Christian P Larsen and Josefina Alber{\'u} and Barbara A Bresnahan and V{\'a}lter Duro Garcia and Jatin Kothari and Philippe Lang and Eduardo Mancilla Urrea and Philippe Massari and Guillermo Antonio Mondrag{\'o}n-Ram{\'i}rez and Rafael Reyes-Acevedo and Kathleen Rice and Lionel P E Rostaing and S Steinberg and Jun Xing and Mamta Agarwal and Mary Beth Harler and Beth Charpentier},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2012},
  volume={12 1},
  pages={210-7}
}
The clinical profile of belatacept in kidney transplant recipients was evaluated to determine if earlier results in the BENEFIT study were sustained at 3 years. BENEFIT is a randomized 3 year, phase III study in adults receiving a kidney transplant from a living or standard criteria deceased donor. Patients were randomized to a more (MI) or less intensive (LI) regimen of belatacept, or cyclosporine. 471/666 patients completed ≥3 years of therapy. A total of 92% (MI), 92% (LI), and 89… CONTINUE READING

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