Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder.

@article{Kupka2007ThreeTM,
  title={Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder.},
  author={Ralph Werner Kupka and Lori L. Altshuler and Willem A. Nolen and Trisha M Suppes and David A. Luckenbaugh and Gabriele S. Leverich and Mark A. Frye and Paul E. Keck and Susan L McElroy and Heinz Grunze and Robert M Post},
  journal={Bipolar disorders},
  year={2007},
  volume={9 5},
  pages={531-5}
}
OBJECTIVES To assess the proportion of time spent in mania, depression and euthymia in a large cohort of bipolar subjects studied longitudinally, and to investigate depression/mania ratios in patients with bipolar I versus bipolar II disorder. METHODS Clinician-adjusted self-ratings of mood were completed daily for one year for naturalistically treated outpatients with bipolar I (n = 405) or bipolar II (n = 102) disorder. Ratings were analyzed for mean time spent euthymic, depressed, manic… CONTINUE READING

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