Three sequence rules for chromatin.

  title={Three sequence rules for chromatin.},
  author={Amir B. Cohanim and Yechezkel Kashi and Edward N. Trifonov},
  journal={Journal of biomolecular structure & dynamics},
  volume={23 5},
Extensive DNA sequence analysis of three eukaryotes, S. cerevisiae, C. elegans, and D. melanogaster, reveals two different AA/TT periodical patterns associated with the nucleosome positioning. The first pattern is the counter-phase oscillation of AA and TT dinucleotides, which has been frequently considered as the nucleosome DNA pattern. This represents the sequence rule I for chromatin structure. The second pattern is the in-phase oscillation of the AA and TT dinucleotides with the same… CONTINUE READING