Three recessive genes for congenital osteopetrosis in Norway rat.

@article{Moutier1976ThreeRG,
  title={Three recessive genes for congenital osteopetrosis in Norway rat.},
  author={Ren{\'e} Moutier and Keisuke Toyama and William R. Cotton and Joanna Gaines},
  journal={The Journal of heredity},
  year={1976},
  volume={67 3},
  pages={189-90}
}
In the rat, the autosomal recessive toothless (t1) mutation exhibits an acute form of osteopetrosis. This gene is not an allele of either ia or op that causes respectively, a transitory and acute form of the disease. Comparative radiographic study of t1/t1 and op/op mutants reveals some differences in respect to the size and shape of long bones. In contrast to op/op mutants, homozygous t1/t1 animals failed to respond to either parabiosis or bone marrow transplants.