Three patterns of cytochrome P450 gene expression during liver maturation in mice.

@article{Hart2009ThreePO,
  title={Three patterns of cytochrome P450 gene expression during liver maturation in mice.},
  author={Steven N. Hart and Yue Cui and Curtis D. Klaassen and Xiao-bo Zhong},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  year={2009},
  volume={37 1},
  pages={116-21}
}
The neonatal period of liver development is an often overlooked phase of development. For instance, ontogeny of xenobiotic-metabolizing enzymes can markedly affect biotransformation as the liver matures. To systematically examine the ontogenic gene expression patterns of cytochrome P450 genes (P450) in mice, the gene expression profiles of 19 xenobiotic… CONTINUE READING